Publications in computational biology


Predicting DNA recognition by Cys2His2 zinc finger proteins
Anton Persikov, Robert Osada and Mona Singh. Bioinformatics (2008) in press.

Organization of physical interactomes as uncovered by network schemas
Eric Banks, Elena Nabieva, Bernard Chazelle and Mona Singh. PLOS Computational Biology (2008) 4(10): e1000203. (First two authors equal contribution.)

NetGrep: fast network schema searches in interactomes
Eric Banks, Elena Nabieva, Ryan Peterson and Mona Singh. Genome Biology (2008) 24: 1473--1480.

Characterization and prediction of residues determining protein functional specificity
John A. Capra and Mona Singh. Bioinformatics (2008) 24: 1473--1480.

Predicting functionally important residues from sequence conservation
John A. Capra and Mona Singh. Bioinformatics (2007) 23: 1875--1882.

A combinatorial optimization approach for diverse motif finding applications
Elena Zaslavsky and Mona Singh. Algorithms for Molecular Biology (2006) 1: 13.

A compact mathematical programming formulation for DNA motif finding
Carl Kingsford, Elena Zaslavsky and Mona Singh. Proceedings of 17th Annual Symposium on Combinatorial Pattern Matching (2006) July 5-7; Barcelona, Spain. Berlin, Germany: Springer Lecture Notes in Computer Science. p 233--245.

Predicting protein secondary and supersecondary structure
Mona Singh. Handbook of Computational Molecular Biology, Srinivas Aluru (Editor), Chapman & Hall CRC Computer and Information Science Series, 2005, in press.
Whole-proteome prediction of protein function via graph-theoretic analysis of interaction maps
Elena Nabieva, Kam Jim, Amit Agarwal, Bernard Chazelle and Mona Singh. Bioinformatics (2005) 21 Suppl 1:i302–i310. (ISMB 2005 Best student paper award for Elena Nabieva, 426 papers submitted, 56 accepted, 4 best paper awards.)

Solving and analyzing side-chain positioning problems using linear and integer programming
Carl Kingsford, Bernard Chazelle and Mona Singh. Bioinformatics (2005) 21: 1028–1036. (Advance access publication on 11/16/2004.)

Comparative analysis of methods for representing and searching for transcription factor binding sites
Robert Osada, Elena Zaslavsky and Mona Singh. Bioinformatics (2004) 20: 3516–3525. (Advance access publication on 8/5/2004.)

A novel method for estimating ancestral amino acid composition and its application to proteins of the Last Universal Ancestor
Dawn Brooks, Jacques Fresco and Mona Singh. Bioinformatics (2004) 20(14): 2251–2257. (Advance access publication on 4/8/2004.)

A semidefinite approach to side-chain positioning with new rounding schemes
Bernard Chazelle, Carl Kingsford and Mona Singh. (Authors alphabetized.) INFORMS Journal on Computing, Special Issue on Computational Molecular Biology/Bioinformatics, (2004) 16: 380–392.

A cross-genomic approach for systematic mapping of phenotypic traits to genes
Kam Jim, Kush Parmar, Mona Singh and Saeed Tavazoie. (Authors alphabetized.) Genome Research (2004) 14: 109–115.

Predicting specificity in bZIP coiled-coil protein interactions
Jessica Fong, Amy Keating and Mona Singh. Genome Biology (2004) 5(2): R11.

Evolution of amino acid frequencies in proteins over deep time: Inferred order of introduction of amino acids into the genetic code
Dawn Brooks, Jacques Fresco, Arthur Lesk and Mona Singh. Molecular Biology and Evolution (2002) 19(10): 1645–1655.

The trimer-of-hairpins motif in viral membrane-fusion proteins: Visna virus
Vladimir Malashkevich, Mona Singh and Peter S. Kim. Proc. Natl. Acad. Sci. USA (2001) 98: 8502–8506.

Towards predicting coiled-coil protein interactions
Mona Singh and Peter S. Kim. Proceedings of the 5th Annual International Conference on Computational Molecular Biology (RECOMB); 2001 Apr 22–25; Montreal, CA. New York, NY: ACM. p 279–286.

Structural characterization of the human respiratory syncytial virus fusion protein core
Xun Zhao, Mona Singh, Vladimir Malashkevich, and Peter S. Kim. Proc. Natl. Acad. Sci. USA (2000) 97: 14172–14177.

LearnCoil-VMF: Computational evidence for coiled-coil-like motifs in many viral membrane-fusion proteins
Mona Singh, Bonnie Berger, Peter S. Kim. J. Mol. Biol. (1999) 290(5): 1031–1041.

Computational learning reveals coiled coil-like motifs in histidine kinase linker domains
Mona Singh, Bonnie Berger, Peter S. Kim, James M. Berger and Andrea G. Cochran. Proc. Natl. Acad. Sci. USA (1998) 95: 2738–2743.

An iterative method for improved protein structural motif recognition
Bonnie Berger and Mona Singh. J. Comput. Biol (1997) 4:261–273. (Authors alphabetized.)