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Part of the PICASso program |
| When a foreign substance is introduced into our bodies, our immune system acts to neutralize that substance. This is a complex process involving the collective and coordinated response of approximately 1012 cells. In the effort to fit detailed experimental
findings into a comprehensive model of the immune system, computer models and
simulations are just beginning to play a role.
Computational Immunology Research at Princeton University |
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IMMSIM is an in machina cellular automata model of the humoral and cellular immune responses. |
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Modeling germinal center dynamics and affinity maturation. |
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Using mathematical modeling and computer simulation to estimate hypermutation rates and other biologically relevant parameters from clonal trees derived from experimental micro-dissections. |
©2003 Steven Kleinstein
